Research Compounds
RESEARCH PURPOSES ONLY
All products sold by AbsoluteBioLab are strictly for laboratory and research purposes only. They are not intended for human consumption, diagnosis, treatment, prevention or cure of any disease. Not for veterinary use. By purchasing from us, you confirm you are a qualified researcher.
AbsoluteBioLab supplies high-purity specialist research agents—including Semax, Selank, Melanotan II, and PT-141—exclusively to UK laboratories and academic institutions. Every batch is HPLC-verified (≥99.0% purity) and dispatched domestically from our secure UK facility.
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Receptor Selectivity & Comparative Biochemistry
The compounds catalogued within this research series span three distinct mechanistic classes: melanocortin receptor agonists, neuropeptide anxiolytics, and multi-target regenerative blends. Understanding their divergent receptor pharmacology is essential for designing rigorous in vitro and in vivo experimental protocols. The table below provides a structured comparative overview of each compound's primary molecular targets, formula, mass, and principal research application.
| Compound | Primary Receptor Target | Molecular Formula | Molecular Mass (Da) | Primary Research Focus |
|---|---|---|---|---|
| Semax 10mg | MC4R (melanocortin-4); BDNF/TrkB pathway modulation | C37H51N9O10S | 813.92 | Cognitive enhancement, neuroprotection, BDNF upregulation in rodent models |
| Selank 10mg | GABAergic modulation; IL-6 / serotonin pathway interaction | C33H57N11O9 | 751.88 | Anxiolytic behaviour, immune modulation, memory consolidation in preclinical models |
| Melanotan I 10mg | MC1R (melanocortin-1); non-selective MC agonist | C78H111N21O19 | 1646.85 | Melanogenesis, photoprotection research, pigmentation pathway studies |
| Melanotan II 10mg | MC1R, MC3R, MC4R, MC5R (broad melanocortin agonism) | C50H69N15O9 | 1024.18 | Melanocortin axis research, appetite regulation, erectile function models |
| Klow 80mg | Multi-target: GHSRb (BPC-157), actin/thymosin β4 (TB-500), GHK-Cu (copper-binding growth factor receptor), FPR2/ALX (KPV) | Proprietary blend (4 peptides) | Combined ~14,200 (blend) | Tissue regeneration, anti-inflammatory signalling, wound healing, angiogenesis research |
All compounds are supplied strictly for in vitro and in vivo laboratory research purposes only. Not for human consumption. See our research use policy for full details.
Reconstitution & Laboratory Handling Protocols
All compounds in this catalogue are supplied as lyophilised (freeze-dried) powders, a format that confers maximum long-term stability by eliminating aqueous degradation pathways. Correct reconstitution technique is critical to preserving peptide integrity, preventing aggregation, and ensuring reproducible experimental dosing. The following protocols reflect current best practice for research-grade peptide handling.
Storage Prior to Reconstitution
Lyophilised vials should be stored at −20 °C in a frost-free freezer, protected from light and moisture. Prior to opening, allow the sealed vial to equilibrate to room temperature (approximately 20–22 °C) for a minimum of 15 minutes. This prevents condensation from forming on the lyophilised cake, which can introduce uncontrolled hydration and compromise the powder's structural integrity. Do not open vials in humid environments; a laminar flow hood or equivalent clean-air environment is strongly recommended.
Reconstitution Solvent Selection
For the majority of peptides in this catalogue — including Semax, Selank, Melanotan I, and Melanotan II — bacteriostatic water (0.9% benzyl alcohol in sterile water for injection) is the preferred reconstitution vehicle for stock solutions intended for repeated use. Sterile water for injection (WFI grade) is acceptable for single-use preparations. Acetic acid (0.1–1.0% v/v) may be required for peptides with poor aqueous solubility at neutral pH; however, this is not typically necessary for the compounds listed herein. Avoid phosphate-buffered saline (PBS) as the primary reconstitution vehicle, as phosphate ions can form insoluble complexes with certain peptide sequences under specific temperature conditions.
Reconstitution Technique
Using a sterile insulin syringe or equivalent low-dead-volume syringe, introduce the reconstitution solvent slowly by directing the stream against the inner glass wall of the vial rather than directly onto the lyophilised cake. This minimises mechanical disruption of the peptide matrix. A typical working concentration of 1–2 mg/mL is appropriate for most experimental applications. Gently swirl — do not vortex — the vial until the lyophilised material is fully dissolved. Vortexing introduces shear forces that can induce peptide aggregation and fibrillation, particularly in longer-chain sequences. Allow 2–5 minutes for complete dissolution before use. Reconstituted solutions should be stored at 4 °C and used within 28 days; for longer storage, aliquot into single-use volumes and store at −80 °C.
Handling Multi-Peptide Blends
Operational Decision: Co-Lyophilisation of KLOW
Our multi-peptide blend KLOW (containing BPC-157, TB-500, GHK-Cu, and KPV) requires precise stoichiometric balancing to prevent competitive receptor binding. We chose to manufacture KLOW using a proprietary co-lyophilisation technique where all four peptides are dissolved in a single solvent system and freeze-dried simultaneously, ensuring a perfectly uniform distribution in every single vial. This approach eliminates the inter-vial variability that would arise from blending individual lyophilised powders post-manufacture — a critical consideration when experimental reproducibility depends on consistent molar ratios across all four active constituents.
When reconstituting Klow 80mg, the co-lyophilised matrix dissolves as a unified system; researchers should therefore apply the same gentle reconstitution technique described above, using bacteriostatic water as the preferred vehicle. Because the four constituent peptides — BPC-157, TB-500, GHK-Cu, and KPV — have been co-processed, no sequential addition or pH adjustment is required. The resulting solution should be clear to slightly opalescent; any visible particulate matter or turbidity should be regarded as a sign of degradation, and the vial should not be used.
Downstream Dilution & Filtration
For cell culture applications, reconstituted peptide stock solutions should be sterile-filtered through a 0.22 µm low-protein-binding membrane (e.g., PVDF or PES) prior to addition to culture media. Note that certain peptides — particularly those with high hydrophobicity indices — may exhibit non-specific adsorption to filter membranes; in such cases, pre-wetting the filter with a small volume of the reconstituted solution and discarding the first pass is advisable. All dilutions should be prepared fresh on the day of the experiment where possible.
AbsoluteBioLab is a registered supplier of laboratory research
compounds in the United Kingdom
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info@absolutebiolab.co.uk
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07756625584
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UK-based facility
RESEARCH PURPOSES ONLY
All products listed on this website are sold strictly as Research Use Only (RUO) chemical
reagents. They are intended solely for in vitro laboratory research, analytical testing, and
preclinical scientific investigation conducted by qualified personnel in controlled
environments. These products have not been evaluated, authorized, or licensed by the
Medicines and Healthcare products Regulatory Agency (MHRA) or any equivalent global
body for use in humans or animals. They are not intended for human consumption,
diagnosis, treatment, prevention, or cure of any disease or medical condition.
AbsoluteBioLab does not provide dosing, administration, or therapeutic guidance. Any
purchase or use of these compounds outside the strict boundary of laboratory research
constitutes a breach of our terms of supply.
AbsoluteBioLab is a registered supplier of laboratory research
compounds in the United Kingdom
Quick Links
Get in Touch
info@absolutebiolab.co.uk
24hr response
07756625584
Mon–Fri, 9am–6pm GMT
Birmingham, United Kingdom
UK-based facility
